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She is the fifth pharaoh of Ancient Egypt's 18th dynasty and is one of the most celebrated and successful rulers during her time. http://en.wikipedia.org/wiki/Hatshepsut

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Born in the 15th century BC, Hatshepsut, daughter of Tuthmose I and Aahmes, both of royal lineage, was the favorite of their three children. When her two brothers died, she was in the unique position to gain the throne upon the death of her father. To have a female pharaoh was unprecedented, and probably most definitely unheard of as well. When Tuthmose I passed away, his son by the commoner Moutnofrit, Tuthmose II, technically ascended the throne. For the few years of his reign, however, Hatshepsut seems to have held the reins. From markings on his mummy, archaeologists believe Tuthmose II had a skin disease, and he died after ruling only three or four years. Hatshepsut, his half sister and wife, had produced no offspring with him (her daughter Nefrure was most likely the daughter of her lover Senmut), although he had sired a son through the commoner Isis. This son, Tuthmose III, was in line for the throne, but due to his age Hatshepsut was allowed to reign as queen dowager.